unfortunally it sounds like the engine control unit,but i would carry out a compression test on the cylinders incase your head gasket has failed or you have burnt out valve first.the other thing to check is the catalytic converter is not broken up or blocked.
i hope this helps,craig.
I have the same problem and i have had it serviced by vauxhall and changed coil pack no change did you manage to fix it, my zafira 1.6 16v is a 2006 its booked in with vauxhall tomorrow there gona charge me a bomb, my fault codes were 0303 and 0300 cylinder 3 misfiring.
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